Blepharospasm


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What Is Blepharospasm?

  • Blepharospasm is a neurological movement disorder, characterized by involuntary and sustained contractions of the muscles around the eyes, especially of the orbicularis oculi muscle.
  • As it is limited to one region of the body, blepharospasm is classified as a focal dystonia.
  • The disease is also called Benign Essential Blepharospasm (BEB); the term 'essential' indicates that the exact cause is unknown.
  • Patients experience impaired quality of life and, in severe cases, can suffer from functional blindness.

 

Symptoms

  • Excessive blinking
  • Watering eyes
  • Light sensitivity
  • Dry eyes
  • Eye irritation

 

 

 

What Is the First Line Treatment for BEB?

The first line treatment is botulinum neurotoxin type A, e.g., XEOMIN®, which reduces disease symptoms by reducing involuntary and sustained contractions of the muscles around the eyes and enables most patients to resume a relatively normal life when administered regularly.

How XEOMIN® Works?

In adults with blepharospasm, nerve signals tell the muscles to contract when they shouldn’t. This can cause eyelid movement that leads to discomfort.

XEOMIN® is injected into muscles to help interfere with these signals. This helps decrease eyelid spasms.

Some muscles may still contract, but less severely.

 

Muscles Involved in Blepharospasm

 

Dosing Frequency

 

Injection Sites

 



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