* FDA approved in 2010 for use in the United States for cervical dystonia and blepharospasm in adults. * FDA approved in 2015 for use in the United States for upper limb spasticity in adults. * Approved in Europe for cervical dystonia and blepharospasm since 2005 and approved for post-stroke ULS in Europe since 2009. * Approved in Canada for cervical dystonia, blepharospasm, and ULS since 2009. * Used in 49 countries worldwide. * Studied in clinical trials worldwide, which involved: * More than 400 adult patients with upper limb spasticity,including patients who had been previously treated and patients who were new to neurotoxin therapy * Nearly 600 patients with cervical dystonia * Nearly 400 patients with blepharospasm
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